Usually a brilliant scientist, a sophisticated billionare or a superhuman being with advanced technology, this is someone who wears a mechanical suit or armor to upgrade an aspect of their body. This also includes villains who have replaced parts of their body with mechanical parts i.e. cyborgs.

This category often coincides with Gadgeteers but differs by the fact that Gadgeteers almost exclusively use their own inventions whilst Mechanically Modified beings may utilize stolen technology (such as Apocalypse) and are usually dependent upon their advanced technology, without which they are severely weakened (unlike many Gadgeteers, who are smart enough to survive even without their "toys").